The Generally Recognized Safety of Dimethyl Sulfoxide (DMSO) in Human-Use Medical Applications
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Dimethyl Sulfoxide (DMSO) is FDA approved as the active ingredient in Mylan’s “RIMSO-50”:
https://www.hipaaspace.com/medical_billing/coding/national.drug.codes/67457-177-50
The FDA has approved DMSO as an inactive ingredient for intravenous, subcutaneous, and topical (both lotion and solution) delivery routes. Search the FDA’s inactive ingredient database for Dimethyl Sulfoxide here:
https://www.accessdata.fda.gov/scripts/cder/iig/index.cfm
PENNSAID is one example of an FDA approved topical drug-using DMSO to increase transdermal absorption:
https://www.pennsaid.com/targeted-oa-knee-pain-relief
For use in these FDA approved applications, the Gaylord Chemical Company produces high purity DMSO under the trade name “Procipient” in their FDA-inspected facility:
https://www.gaylordchemical.com/products/product-grades/procipient/
From that page:
“DMSO is essentially non-toxic by all routes of administration. It is well tolerated by oral and dermal route of delivery as well as subcutaneous and intramuscular delivery.”
DMSO is also FDA approved for use in horses and dogs, and Zoetis produces it under the trade name “Domoso”:
https://www.drugs.com/vet/domoso-solution.html
For further reading:
- https://www.rxlist.com/dmso_dimethylsulfoxide/supplements.htm
- https://pubmed.ncbi.nlm.nih.gov/22030943/
- https://www.pharmtech.com/view/advances-regulated-pharmaceutical-use-dimethyl-sulfoxide-usp-pheur
There are a large number of books that advocate human use of DMSO:
- Dimethyl Sulfoxide (DMSO) in Trauma and Disease by Stanley W. Jacob
- The DMSO Handbook: A New Paradigm in Healthcare by Dr Hartmut Fischer
- DMSO Handbook: A Complete Guide to the History and Use of DMSO by Bruce Halstead
- The DMSO Handbook for Doctors by Archie H. Scott
- DMSO: Nature’s Healer by Morton Walker
- DMSO: THE UNIVERSAL HEALER by Dr. Kendra Nathan
- THE HEALING WONDERS OF DMSO by Dr. Marylyn G. Andrea
- HEALING PROPERTIES OF DMSO by Eric Goldinger
- NATURAL REMEDY DMSO: A MIRACLE DRUG by Lata Dorella
- DMSO Treatments by Thomas Henry
- EVERYTHING YOU NEED TO KNOW ABOUT DMSO by Matilda Sean
- DMSO: Nature’s Universal Healer by Dr. Patricia W. Alex
- DMSO: THE UNIVERSAL HEALING WONDER by Dr. Steven Carson
- BEGINNERS GUIDE TO HEALING WITH DMSO by Lisa H. Gregory Ph.D
- DMSO: The True Story of a Remarkable Pain Killing Drug by Barry Tarshis
- DMSO: Responsible User’s Guide by Thomas Bristol
- Benefits Of Drinking DMSO by Rudolf Spara
- Optimal Healing with DMSO by Wendy Sullivan MD
- Persecuted Drug: The Story of DMSO by Pat McGrady
- DMSO: The Unique All-Time Healer by Dr. Isaac Joe
- New Method Of Healing With DMSO by Williams Evelyn
- Holistic Healing with DMSO by Dr. Elizabeth David
- Healing with DMSO by Dr. Tracy Brian
- Simplified Guide To Healing With DMSO by Enedino Smith
These companies produce DMSO nominally as a solvent for legal/regulatory reasons, but commonly used for human medical purposes:
- Jacob Laboratories: https://www.jacoblab.com/
- Nature’s Gift: https://naturesgift-dmso.com/
- DMSO Store: https://dmsostore.com/
- Biogenic Foods: https://biogenicfoods.com/dmso-dimethyl-sulfoxide-pharmaceutical-grade-99-999-pure-undiluted-usa-produced/
- Heiltropfen: https://www.heiltropfen.de/shop/en/21-dmso